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Endomorphin-1 The heterogeneity among studies that investiga
2021-02-04
The heterogeneity among studies that investigated the association of COMT Val158Met with alexithymia was also significant (Ham et al., 2005; Min et al., 2016; Swart et al., 2011; Zekioglu et al., 2014). The healthy status, drug effect, and other demographic variables also influenced one's ability of
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The enzymatic activity of recombinant sponge P
2021-02-04
The enzymatic activity of recombinant sponge P4H was assayed in vitro both at 37°C, the standard enzymatic kinetics temperature, and at 15°C, the typical sea temperature of C. reniformis marine environment (Fig. 2C). Surprisingly the data obtained indicate that the sponge enzyme has a lower activity
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br Conclusion and future perspectives LDL cholesterol loweri
2021-02-04
Conclusion and future perspectives LDL cholesterol-lowering therapy is essential for cardiovascular risk reduction. On the background of a high inter-personal variation of cholesterol synthesis and cholesterol doripenem the efficacy of cholesterol lowering, both, with statins and with ezetimibe
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It is well known that Doxorubicin induced cardiotoxicity occ
2021-02-04
It is well known that Doxorubicin-induced cardiotoxicity occurs via p53-mediated apoptosis (Lorusso et al., 2007). However, there are few studies elucidating the mechanism of HFS induced by PLD. We found that PLD induces keratinocyte apoptosis in a very low dose, and the damage induced by PLD cannot
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It is well established that a number
2021-02-04
It is well established that a number of intracellular signaling pathways mediate sensitization of sensory neurons (Gold and Gebhart, 2010, Richardson and Vasko, 2002). This redundancy could be advantageous since it provides diversity in initiating and maintaining hypersensitivity in response to inju
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br The synthesis of these antagonists
2021-02-04
The synthesis of these antagonists relied heavily on Stille and Suzuki coupling reactions. The preparation of the required building blocks is presented in . Reduction of ethyl 6-bromo-2-pyridinecarboxylate with diisobutylaluminum hydride in tetrahydrofuran followed by treatment with triisopropylsi
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Yu et al also reported that extracting consortium of hydroly
2021-02-04
Yu et al. [24] also reported that extracting consortium of hydrolytic enzymes from sludge flocs performs better than costly single purified commercial enzyme. Thus, it is concluded from the above cited literature analysis that only few studies have been reported on extraction of enzymes from waste s
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Enhanced responses to varying concentrations of bronchoconst
2021-02-04
Enhanced responses to varying concentrations of bronchoconstrictors, such as MCh, and airway obstruction are characteristic of Nepicastat HCl and common to other clinical states, including chronic obstructive pulmonary disease, lung transplantation, and infection- or chemical agent-induced airway i
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br Results br Discussion The origin and fate of
2021-02-04
Results Discussion The origin and fate of Tfh cells has been intensely studied since their first description 14 years ago (Breitfeld et al., 2000, Schaerli et al., 2000). Although mice engineered to report BCL6 (Kitano et al., 2011, Liu et al., 2012) and interleukin-21 (IL-21) (Lüthje et al.,
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br The ubiquitin proteasome system The ubiquitin proteasome
2021-02-04
The ubiquitin proteasome system The ubiquitin proteasome system (UPS) plays a significant role in the regulation of cell growth and survival, in addition to maintaining cellular homeostasis. By means of the UPS, KB SRC 4 synthesis can precisely and temporally degrade approximately 80% of the enti
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br Acknowledgments This work was supported by Grants
2021-02-04
Acknowledgments This work was supported by Grants from the National Research Foundation (2010-0000782) and the National Center for GM Crops (PJ008152) of the Next Generation BioGreen 21 Program funded by the Rural Development Administration, Republic of Korea, to W.T.K. Introduction Ubiquityl
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Additionally we analysed the features
2021-02-03
Additionally, we analysed the features of apomict and sexual Boechera species DNMT proteins. All DNMT proteins showed highly similar theoretical pI, molecular weight and predicted sub-cellular localization (Table 2). Discussion Identification of the structure and expression levels of DNMTs durin
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Nowadays colorimetric assay has been applied in detecting DN
2021-02-03
Nowadays, colorimetric assay has been applied in detecting DNA MTase activity. Li et al. used DNA modified gold nanoparticles (AuNPs) coupled with enzyme-linkage reactions to detect the activity of methylases [20]. In a previous study, our group presented a label-free colorimetric method, using unmo
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br Conclusion br Funding source br Ethical
2021-02-03
Conclusion Funding source Ethical approval Conflict of interest statement Introduction Traditionally, schizophrenia (SZ) was thought to be associated with neuronal dysfunction; however, the current hypothesis that myelin and, specifically, oligodendrocytes are also involved in the dev
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The crystal structure of the
2021-02-03
The crystal structure of the B. subtilis Maf (BSU28050) was published in 2000, and, to date, it represents the only experimental work with a purified Maf protein (Minasov et al., 2000). The structure revealed a structural fold similar to that found in ITPases and YjjX proteins, which are nucleotide
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