• The aim of this study

  2020-07-06

  

  The aim of this study was to use molecular methods to characterise C. difficile isolates circulating in the Czech Republic from 2013 to 2015. Material and methods Discussion During a three-year period (2013–2015) a total of 32 hospitals voluntarily participated in this project, but only 11 ho

• TNKS 49 These data indicate that in the context of the N

  2020-07-06

  

  These data indicate that, in the context of the N-terminal 42 amino acids of p53, threonine 18 is a substrate for phosphorylation by CK1 as mediated by prior phosphorylation of serine 15. To determine whether this is a property of full length p53, GST-p53 fusion proteins comprising the full length p

• br Introduction Cell transplantation therapies using embryon

  2020-07-06

  

  Introduction Cell transplantation therapies using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC)-derived retinal tissue (ESC/iPSC retina) or Cy7 maleimide (non-sulfonated) receptor have emerged as therapeutic options for retinal degeneration following recent breakthroughs. A

• br Materials and methods br Results br Discussion The

  2020-07-03

  

  Materials and methods Results Discussion The first DGAT1 gene was described in the mouse in 1998 [28], and a few years later DGAT2 was identified from the oleaginous fungus Mortierella ramanniana[29]. Although both of them are known as the primary enzymes for de novo TAG biosynthesis, they

• dorsomorphin Studies of Jelski and Szmitkowski

  2020-07-03

  

  Studies of Jelski and Szmitkowski show that differences of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activity between dorsomorphin of many cancers and healthy tissue may be one of the factors intensifying carcinogenesis [7]. Moreover, changes of ADH and ALDH activity in cancer ce

• The CPA EoS was presented by Kontogeorgis et al

  2020-07-03

  

  The CPA EoS was presented by Kontogeorgis et al., in 1996 [23]. The proposed equation is composed of two parts (SRK EOS + association term) such that it can well predict the thermodynamic behavior of hydrogen bonding materials as a result of considering the association term. Yakoumis et al. (1997) e

• br Results br Discussion We first tested

  2020-07-03

  

  Results Discussion We first tested for any adverse effect of ATR on learning and memory with a MWM test, which is used to assess hippocampal spatial learning and memory abilities in rodents (Vorhees and Williams, 2006). In the place navigation test, the escape latency – or time spent locating

• br Material and methods br Results and discussion br Conclus

  2020-07-03

  

  Material and methods Results and discussion Conclusions Prostanoid-E receptor selective antagonists that inhibit EP2 or EP4 receptor activities may be used as a pharmacological strategy to limit cyst formation and ADPKD progression. Our study follows on from our previous observations of the

• The loss of secondary mutation T M

  2020-07-03

  

  The loss of secondary mutation T790M mutation after AR and SCLC transformation was also reported for Rociletinib. Piotrowska et al. using the MGH NGS platform recently reported in 13 biopsies among 12 EGFR T790M+ patients progressing after treatment with Rociletinib the loss of EGFR T790M mutation i

• br Materials and methods br

  2020-07-03

  

  Materials and methods Results Metabolic stability of compounds was studied by incubation with pooled human liver microsomes. Piperine was the metabolically most stable compound, with a t1/2 of 141min (Fig. 2, and Table 1). SCT-29 and LAU 397 showed t1/2 of approx. 45min, whereas a t1/2 of only

• Furthermore many intermediate plants did not show additive c

  2020-07-03

  

  Furthermore, many intermediate plants did not show additive combinations of parental allozymes, which would be expected in F1 hybrids. The absence of some characteristic parental bands suggests that sexual reproduction has occurred among the hybrid plants. Genetic variations within and among the int

• br Introduction br Conclusion br Acknowledgments

  2020-07-03

  

  Introduction Conclusion Acknowledgments and Funding Introduction Reversible protein phosphorylation is an important post-translational modification of proteins regulating many processes in the cell. Approximately one third of the cellular proteome is phosphorylated, and several sites are

• br Conclusion and future perspectives LDL cholesterol loweri

  2020-07-03

  

  Conclusion and future perspectives LDL cholesterol-lowering therapy is essential for cardiovascular risk reduction. On the background of a high inter-personal variation of cholesterol synthesis and cholesterol SBI-0206965 the efficacy of cholesterol lowering, both, with statins and with ezetimib

• Resistance to avermectins has been associated with point mut

  2020-07-03

  

  Resistance to avermectins has been associated with point mutations of GluCls in C. elegans, D. melanogaster, T. urticae and P. xylostella (Dent et al., 2000; Dermauw et al., 2012; Kane et al., 2000; Kwon et al., 2010; Wang et al., 2016a, 2017). Our electrophysiological study found a 8.2-fold reducti

• br Genomic actions in the breast

  2020-07-02

  

  Genomic actions in the breast Conclusion Clinical studies suggest that progesterone and/or progestins may play a decisive role in the development of breast cancer in women using hormone therapy or oral contraceptives [3], [4]. However, this data are controversial to most experimental investiga

14371 records 800/959 page Previous Next First page 上5页 796797798799800 下5页 Last page